This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...

The efficiencies with which activated B lymphocytes proliferate and develop into antibody (Ab)- secreting plasma cells are critical determinants of adaptive humoral immunity and central to sustaining ...

This study presents valuable findings by demonstrating that specific GPCR subtypes induce distinct extracellular vesicle miRNA signatures, highlighting a potential novel mechanism for intercellular ...

The study presents valuable theoretical insights by attempting to classify pattern-forming gene subnetworks and exploring their potential mechanisms. However, the results are incomplete, as they rely ...

The study provides valuable technical advances to generate and isolate neural rosettes. The technique is robust, as indicated by both reviewers. The evidence is solid, as shown in orthogonal ...

Studying the growth of bacteria without cell walls in an artificial environment can shed new light on the proliferation of primitive life-forms billions of years ago.

eLife works to improve research communication through open science and open technology innovation ...

Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.

Glaucoma-associated Optineurin mutations increase transcellular degradation of mitochondria in a vertebrate optic nerve ...

Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.

This study examines a valuable question regarding the developmental trajectory of neural mechanisms supporting facial expression processing. Leveraging a rare intracranial EEG (iEEG) dataset including ...

This important study provides evidence for dynamic coupling between translation initiation and elongation that can help maintain low ribosome density and translational homeostasis. The authors combine ...