A research team has discovered a new mechanism and drug combination strategy that can effectively treat osteoporosis, a ...

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix ...

Histology of growth plate cartilage of achondroplasia model mice in which FGFR3 is overactivated. This study identified SPONDIN1 as a marker for CREB activity. Resting zone was expanded and expressed ...

Around 40% of adults worldwide are affected by osteopenia: a loss of bone mineral density. This condition is extremely common ...

Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in the PEPITEM molecule, and demonstrated the biological activity of the full PEPITEM molecule in ...

A bone-like composite developed at EPFL uses naturally occurring enzymes to accelerate mineralization through an energy-efficient, room-temperature process. The strong, lightweight material shows ...

HO or abnormal bone formation in soft tissues can restrict movement and cause long-term discomfort after surgery or injury. In a new study, researchers have identified two key proteins that help ...

Achondroplasia, also known as short-limb dwarfism, is associated with neurological symptoms and complications due to narrowing of the skeletal structures surrounding the spinal cord. Despite ...