At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

A new review in the Journal of Translational Medicine consolidates how the replication-initiation protein ORC1 safeguards ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

A study headed by researchers at NYU Langone Health has found that herpes simplex virus 1 (HSV-1) partially liquifies the tightly packed, gel-like interior of human cell nuclei to help copy itself ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

New research shows that astroviruses, a leading cause of childhood diarrhea, co-opt the mucus-secreting machinery of ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...